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THROMBOXANE A2
Descriptors Found:
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DeCS
Descriptor
English
:
Thromboxane A2
Descriptor
Spanish
:
Tromboxano A2
Descriptor
Portuguese
:
Tromboxano A2
Synonyms
English
:
Rabbit Aorta Contracting Substance
Tree Number:
D10.251.355.255.100.825.800
D10.251.355.310.166.971.800
Definition
English
:
An unstable intermediate between the
prostaglandin endoperoxides
and
thromboxane B2
. The compound has a bicyclic oxaneoxetane structure. It is a potent inducer of
platelet aggregation
and causes
vasoconstriction
. It is the principal component of
rabbit aorta contracting substance
(RCS).
Indexing Annotation
English
:
/biosyn /physiol permitted
History Note
English
:
86(78); was see under THROMBOXANES 1978-85
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
14314
Unique Identifier:
D013928
Occurrence in VHL
:
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